| Product Name | GS-441524 |
| CAS Number | 1191237-69-0 |
| Dosage Form | Injectable Solution |
| Strength Options | 20mg / 30mg |
| Packaging | 6ml/vial, 8ml/vial, 10ml/vial |
| Shelf Life | 12 Months |
| Storage | Store at room temperature, away from direct sunlight |
| Origin | China |
GS-441524 is a widely studied antiviral nucleoside analog designed to inhibit viral replication at the molecular level. It interferes with the viral RNA synthesis process, effectively blocking the reproduction cycle of the virus. As a key metabolite related to remdesivir, it has demonstrated strong stability and bioactivity in antiviral research, especially in veterinary applications.
GS-441524 works by mimicking natural nucleosides, inserting itself into the viral RNA chain during replication. Once incorporated, it disrupts further elongation of the RNA strand, thereby halting viral proliferation. This mechanism helps limit viral spread within the body and allows the immune system to respond more effectively.
Compared with other antiviral approaches, GS-441524 offers:
GS-441524 has gained significant attention in veterinary use, particularly in the management of Feline Infectious Peritonitis (FIP)—a serious disease caused by mutated feline coronavirus.
FIP mainly affects cats with weakened immune systems and can present in two major forms:
Typical symptoms may include:
Loss of appetite, persistent fever, weight loss, lethargy, breathing difficulty, and in some cases neurological or ocular issues.
By suppressing viral replication, GS-441524 helps control disease progression and supports recovery in affected cats.
Dosage may vary depending on the cat’s condition and veterinary guidance:
Note: Actual dosage should always follow professional veterinary advice.